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Rutin enhances vitamin C activity to scavenge free radicals but can also possess some of this activity on its own

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With several products already in clinical use, such as the light-responsive drug Photofrin 1 and the radiation-enhancing nanodrug Hensify, 2,3 this type of materials are engineered to respond to external (light, 4–6 temperature, 7,8 radiation, 3,9 magnetic field 10–12 and ultrasound 13,14 ) or internal stimuli (pH, 15,16 redox 17 and enzymes 16,18 ), resulting in the induction of direct material-mediated therapeutic effects 16,17,19 or triggering the release of active pharmaceutical ingredients (API)